He realized his life purpose by dedicating his life to supporting the board of directors of the Scleroderma Research Foundation. He also established a foundation that raised $35 million for disease cure research. He devoted himself to finding a cure.Īfter her death, her brother, Bob, wrote and directed “For Hope,” a film inspired by Gay and a monument to her lost spirit. Bob Saget’s sister, Gay, died of scleroderma at age 47.